The main objective of the project is to extend the beneficiary´s production portfolio to new high added value products in line with the long-term strategy of selling high-quality HPP pigments with unique user properties in terms of intensity, stability and quality of final product dyeing, and to achieve other functional properties of these materials to extend the area of their application to the functional adjustment of surfaces of mechanical products, especially in the automotive industry.
Solved colorants, perylenes, also exhibit the ability to interact with air oxygen after the irradiation to generate so-called singlet oxygen (photoactive system) as well as the ability to change its shade (the thermochromic system) under precisely defined conditions.
The photoactivities will be investigated for use in self-cleaning systems aimed at the degradation of monomolecular organic compounds and subsequent microbial attack while maintaining the stability of the carrier polymer systems. Thermochromic properties are based on the change in crystalline structure and intermolecular interactions in the carrier environment. The aim is to propose a process for the incorporation of functionalized perylene compounds into a polymeric matrix intended for surface treatments of engineering products in the form of functional coatings or in the form of a thin polymer film.

The aim of the project is to research and develop unique supplements in the form of capsules or granulates, containing monoglycerides for positive
influence of human microbiom. Such a products are not on the market yet. In the frame of the project will be antimicrobial effect of active ingredients
evaluated on typical patogens as well as physical behaviour of the developed products from dissolution point of view.

The aim of this project is to innovate course Philosophy of Education I, II which is a part of the bachelor branch of philosophy. This innovation will consist in a modification of the course philosophy of education I, II on the base of literature from the era of German idealism. Specifically it means more intensive respect to the significance of the term education (Bildung) in German idealistic philosophy and analysis of the problem of Humboldt´s reform of German university. A part of this project is also three-days stay in library in Jena in Germany (the centre of German idealism). This stay will be used for collecting specific philosophical texts concerning issue of education and university ? especially in respect to German idealism. The aim of this project is to deepen and elucidate our understanding of the tradition of university as a place of the unity of science and education.

Financial managers make decisions on asset and financial structure, expense and income as well as profit distribution. In particular, accounting information provide important support to their decision-making. However, important information on business activities and results are usually stated in verbal rather than in numerical form. The qualitative aspects help not only evaluate the current economic situation of the company but also improve company management and establish its goals. Verbal comments are also important for investors, which use them as a basis to evaluate investment opportunities. To obtain a complete picture of the financial situation, the context-sensitive information provided in various sources of text documents is thus necessary. Therefore, understanding how the information in the documents can be used to predict financial indicators is obviously of great importance. The results of this research will shed light on the role of opinion expressed by various insiders/outsiders in corporate financial decision-making.

Corporate financial distress prediction models are recognized as important early warning systems for corporate stakeholders.
Most research to date has focused on the use of financial ratios as determinants of corporate financial distress, whereas little
attention has been given to the role of qualitative information hidden in reports and news databases. Our objective is to test the
following hypotheses: (1) the use of qualitative text information results in significantly more accurate corporate financial
distress prediction models, and (2) the effect of qualitative information differs across countries and industries. Even if this work
does not support these hypotheses, the understanding of the role of text information in corporate financial distress prediction
will be greatly increased. This study is unique in that it will combine quantitative financial ratios with qualitative information
related to a company in prediction models, allowing quantitative-qualitative relations explicitly coupled to individual countries
and industries.

The aim of the project is proof of concept of the technology for development of a new combined drug with paracetamol. This new pharmaceutical product will possess lower toxicity in comparison with other products. The use of standard pharma-product containing paracetamol can lead to the toxicity in liver and kidney after overdose. Based on our mostly unpublished and unique results, the main aim of present project is to prove our hypothesis on possible defense against this toxicity. The outcome of our project will be: 1) development of a new combined drug product containing paracetamol with lower toxicity 2) followed by commercialization.

The aim of the project is the description of a newly found toxic mechanism of acetaminophen toxicity that contributes to hepatotoxic effect of acetaminophen (APAP); our aim has been stated regarding our published and also unpublished data. After APAP overdose, the specific metabolite is produced in the cell. This compound has been considered as non-toxic. In this project, we intend to synthesize and purify it in sufficient quantity. Consequently, we will use it to detailed study of its effects in cultured hepatocytes in vitro and in vivo in mice and rats.

The objectives of the project are determined in accordance with the "Cultural Heritage" objective of the NAKI II program.
We are developing tools for the protection, identification and presentation of the cultural heritage of the Benedictine order in the Czech Republic,
represented primarily by the monasteries in Broumov and Rajhrad. Special attention will be given to the libraries of each monastery.

Research will focus on the book collections from the Broumov and Rajhrad monasteries and also the space and equipment of the libraries.
The project will develope:
1. Preservation procedure for the protection and care of library collections of monastic libraries,
2. Methodology for care of space, facilities and equipment of Baroque interior libraries, which both of the above mentioned libraries represent.

The result of this project is a database of typographical elements of the books, and special software for usage of this database.
Both will create a platform for further editing, analytical and comparative work with books.
The cultural heritage of both monasteries will be presented to the general and scientific public by making the collections available
and by other presentation activities: exhibitions, videos, scientific books, studies in peer-reviewed journals and anthologies.
At the same time steps will be taken to rescue the book heritage of the Broumov monastery.
We plan to restore the rarest and most vulnerable books. The content of the book collections will be presented in the form of user-friendly maps.

Project will be focused on the development of innovative active and passive materials, ready for practical applications: a) highly sensitive polymer nanocomposite detectors; b) new materials with low density based on polymer nanocomposite materials. Developed materials will find applications not only in the space industry but also other industrial sectors (automotive, aerospace, defensive, healthcare) due to their unique properties .